Bactrim

Generic Bactrim

(Trimethoprim)

Generic Bactrim is an antibacterial medicine applied in treating infections. It is has a broad spectrum activity, thus it is active against a big number of pathogens.

Package
Price
Per Pills
Savings
400/80 mg x 30 pills
$26.99
$0.90
$0.00
Next orders 10% discount
400/80 mg x 60 pills
$43.99
$0.73
$10.20
Next orders 10% discount
400/80 mg x 90 pills
$58.99
$0.66
$21.60
Next orders 10% discount
400/80 mg x 120 pills
$70.99
$0.59
$37.20
Next orders 10% discount
400/80 mg x 180 pills
$95.99
$0.53
$66.60
Next orders 10% discount
400/80 mg x 270 pills
$128.99
$0.48
$113.40
Next orders 10% discount
400/80 mg x 360 pills
$154.99
$0.43
$169.20
Next orders 10% discount
Package
Price
Per Pills
Savings
800/160 mg x 10 pills
$18.99
$1.90
$0.00
Next orders 10% discount
800/160 mg x 20 pills
$31.99
$1.60
$6.00
Next orders 10% discount
800/160 mg x 30 pills
$43.99
$1.47
$12.90
Next orders 10% discount
800/160 mg x 60 pills
$78.99
$1.32
$34.80
Next orders 10% discount
800/160 mg x 90 pills
$106.99
$1.19
$63.90
Next orders 10% discount
800/160 mg x 120 pills
$128.99
$1.07
$99.60
Next orders 10% discount
800/160 mg x 180 pills
$173.99
$0.97
$167.40
Next orders 10% discount
800/160 mg x 360 pills
$311.99
$0.87
$370.80
Next orders 10% discount
+ Free standard airmail service
Product Description

Generic Bactrim is an antibacterial drug used to treat infections. It is has a broad spectrum activity, thus it is active against a big number of pathogens.

Generic Bactrim has 2 active substances: trimethoprin and sulphametoxazole. They act sinergetically by blocking two enzymes which catalyse consecutive phases of folinic acid biosynthesis. This mecanism has an in vitro bactericide action over a big number of gram-positive and gram-negative bacteria (more than 75% of sensible strains): Enterobacter spp., Acinetobacter spp., Salmonell typhi, Toxoplasma gondii etc. In situations when the infection is caused by partially sensible pathogens, it is recommended to pass a sensibility test in order to exclude any resistance.

Common use

Generic Bactrim is used to treat:

  1. superior and inferior respiratory tract: acute and chronic bronchitis, pneumonia, pharyngitis, tonsillitis, sinusitis, otitis
  2. urinal tract infections: acute and chronic cystitis, pyelonephritis, urethritis, prostatitis
  3. genital infections for both men and women, such as: gonococcal urethritis
  4. gastrointestinal tract, including typhoid and paratyphoid fever and for the treatment of chronic carriers
  5. skin and soft tissues infections: pyoderma, furunculous and infected wounds
  6. other bacterial infections: acute and chronic osteomyelitis, acute brucellosis, septicemia due to sensible organisms, mycetoma, South American blastomycosis.

Administration and dosage

Bactrim should be taken once in 12 hours. Adults and children over 12 years are prescribed this drug in pills. For children under 12 years the more appropriate form would be the syrup.

Precautions and warnings

Generic Bactrim should be administered very carefully, in accordance with the health care provider, in patients with severe haematological disorders. In order to reduce the risk of side effects elder patients will take this drug for a short period. People with G6PD dysfunction will take this drug only if this is absolutely necessary, with the lowest doses possible.

Pregnancy and breastfeeding. Bactrim is forbidden during pregnancy and in the first weeks of baby’s live. Afterwards, even though trimethoprin and sulphametoxazole pass into mother’s milk, it is not considered to be a risk factor.

Patients who are under Generic Bactrim for a long period of time (especially those with kidney failure) will check their urine and kidney function on a regular basis.

Contraindications:

Bactrim is contraindicated for:

  1. people with severe affections of liver parenchyma
  2. people allergic to one or both active substances
  3. people with severe kidney failure when plasma concentration tests cannot be made regularly
  4. elder patients- there is a high risk of severe side effects if patients have liver and/or kidney disorders or if they use some other drugs at the same time (the risk depends on the dosage and treatment duration)
  5. people with Stevens-Johnson syndrom, Lyell syndrom and fulminant liver necrosis
  6. children under 6 years, if Bactrim is to be administered intramuscularly. The reason for this is a reduced muscle mass.

Generic Bactrim Side effects

If it taken as prescribed Bactrim is usually well tolerated. Even if side effects appear, they are not severe. Thus, we can mention some of them:

  1. gastrointestinal tract: nausea (with or without vomiting), diarrhea, rare cases of hepatitis, stomatitis
  2. skin erruptions: usually these are not severe and pass as soon as the medication stops being administered
  3. leukopenia, neutropenia, thrombocytopenia
  4. cough and breathing difficulties

Drug interaction

Generic Bactrim may interact with:

  1. some diuretic drugs, especially thiazides- mainly elder patients have noticed an increased incidence of thrombocytopenia
  2. anticoagulants like warfarin- Generic Bactrim may prolong the prothrombin time. This will be taken into consideration when Bactrim is prescribed to patients under anticoagulants therapy
  3. phenytoin- Generic Bactrim may hinder the hepatic metabolism of phenytoin
  4. hypoglycaemic drugs- Generic Bactrim may have an incidence over the recommended dose

Missed dose

If you missed one dose of Bactrim, take as soon as you remember about it and all of the next doses should be adminstered within a 12 hours interval.

Overdose

In case of an overdose please see your doctor or go to the nearest hospital immediately.